All publications


  1. Ludovini V.*, Bianconi F.*, Siggillino A., Piobbico D., Vannucci J., Metro G., Chiari R., Bellezza G., Puma F., Della Fazia MA., Servillo G., Crinò L., “Gene identification for risk of relapse in stage I lung adenocarcinoma patients: a combined methodology of gene expression profiling and computational gene network analysis.”, Oncotarget, 2016 Apr 13
  2. Vannucci J., Droghetti A., Bufalari A., De Monte V., Bellezza G., Bianconi F., Pecoriello R., Daddi N., Moriconi F., Puma F.,“Effectiveness and predictability of pleurodesis with the TachosilÂo surgical patch compared with talc poudrage: an experimental study.”, Eur J Cardiothorac Surg. 2016 Apr 22.
  3. Bianconi F., Giuseppe M. Masanotti GM., Liso A.,La Rosa F., Duca E., Stracci F., “Seasonal Variation in Skin Cancer Diagnosis.”, Front. Public Health, 28 April 2016
  4. F. Stracci, F. Bianconi, S. Leite, A. Liso, F. La Rosa, V. Lancellotta, C.J.H. van de Velde, C. Aristei, “Linking surgical specimen length and examined lymph nodes in colorectal cancer patients”, European Journal of Surgical Oncology (EJSO) 42.2, 260-265, 2016.
  5. G.M. Masanotti, F. Cioccoloni, F. Stracci, F. Bianconi, E. Duca, F. La Rosa “Cancer burden trends in Umbria region using a joinpoint regression”, Annali dell’Istituto Superiore di Sanitá 51 (3), 209-216, 2015.
  6. F. Bianconi, E. Baldelli, V. Ludovini, E. Petricoin, L. Crinò, P. Valigi, “Conditional robustness analysis for fragility discovery and target identification in biochemical networks and in cancer systems biology”, BMC systems biology, 9 (1), 70, 2015.
  7. A. Flacco, V. Ludovini, F. Bianconi, M. Ragusa, G. Bellezza, FR. Tofanetti, L. Pistola, A. Siggillino, J. Vannucci, L. Cagini, A. Sidoni, F. Puma, M. Varella-Garcia, L. Crinò, “MYC and Human Telomerase Gene (TERC) Copy Number Gain in Early-stage Non-Small Cell Lung Cancer”, American Journal of Clinical Oncology, 38(2), 152-158, 2015.
  8. F. La Rosa, A. Liso, F. Bianconi, E. Duca, F. Stracci. “Seasonal variation in the month of birth in patients with skin cancer”, British journal of cancer 111 (9), 1810-1813, 2014.
  9. F. Bianconi, E. Baldelli, V. Ludovini, L. Crino, K. Perruccio, P. Valigi, “Robustness of complex feedback systems: application to oncological biochemical networks”, International Journal of Control 86 (7), 1304-1321,2013.
  10. V. Ludovini, A. Flacco, F. Bianconi, M. Ragusa, J. Vannucci, G. Bellezza, R. Chiari, V. Minotti, L. Pistola, F. R. Tofanetti, A. Siggillino, E. Baldelli, A. Sidoni, N. Daddi, F. Puma, M. Varella-Garcia, L. Crinò, “Concomitant high gene copy number and protein overexpression of IGF1R and EGFR negatively affect disease-free survival of surgically resected non-small-cell-lung cancer patients”, Cancer Chemotherapy and Pharmacology, Volume 71, Issue 3, pp 671-680, 2013.
  11. G. Bellezza, RD Sordo, R. Colella, V. Ludovini, M. Ragusa, F. Bianconi, I. Ferri, F. Borri, R. Chiari, F. Puma, L. Crinò, A. Sidoni, “Co-expression of receptors of the HER family correlates with clinical outcome in nonsmall cell lung cancer (NSCLC)”, Virchows Archiv, Volume 463, Issue 5, pp 663-671,2013.
  12. M. Ragusa, J. Vannucci, V. Ludovini, F. Bianconi, S. Treggiari, FR. Tofanetti, A. Flacco, R. Colella, A. Sidoni, L. Crinò, F. Puma. “Impact of Epidermal Growth Factor Receptor and KRAS Mutations on Clinical Outcome in Resected Non-Small Cell Lung Cancer Patients”, Am J Clin Oncol, 2013.
  13. D. D’Alò, I. Bernardini, F. Cioccoloni, G. Calagreti, S. Leite, MS. Petrucci, F. Bianconi, V. Brunori,F. La Rosa,F. Stracci F. “Epidemiological characteristics of HPV-related female cancers in the Umbria Region of Italy: pre-vaccination period.” EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, vol. 34, p. 311-318, ISSN: 0392-2936, 2013.
  14. F. Stracci, F. Bianconi, GM. Masanotti, V. Brunori, F. La Rosa, “Effect of healthcare on mortality: trends in avoidable mortality in Umbria, Italy,
    1994-2009” ANNALI DELL’ISTITUTO SUPERIORE DI SANITA’, vol. 49, p. 113-123, ISSN: 0021-2571, 2013.
  15. F. Bianconi, E. Baldelli, V. Ludovini, L. Crinò, A. Flacco and P. Valigi. “Computational model of EGFR and IGF1R pathways in lung cancer: a Systems Biology approach for Translational Oncology”, Biotechnol. Adv., pp. 142-153, 2012.
  16. V.Ludovini, F.Bianconi, L.Pistola, R.Chiari, V.Minotti, R.Colella, FR.Tofanetti, A.Siggillino, A.Flacco, E.Baldelli, D.Giuffrida, D.Iacono, MG. Mameli, A. Cavaliere, L. Crinò. “Phosphoinositide-3-Kinase Catalytic Alpha and KRAS Mutations are Important Predictors of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients with Advanced Non-small Cell Lung Cancer”. Journal of Thoracic Oncology 6 (4), 707-715, 2012.
  17. V. Ludovini, F. Bianconi, L. Pistola, V. Minotti, R. Chiari, R. Colella, G. Bellezza, F. R. Tofanetti, A. Siggillino, E. Baldelli, A. Flacco, D. Giuffrida, A. Sidoni, L. Crinò. “Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of KRAS, PIK3CA, MET, and non-sensitizing EGFR mutations”, Cancer chemotherapy and pharmacology 69 (5), 1289-1299, 2012.
  18. F. Bianconi, V. Brunori, P. Valigi, F. La Rosa, F. Stracci, “Information technology as tools for cancer registry and regional cancer network integration”, IEEE transactions on systems man and cybernetics part a-systems and humans, Volume: 42, Issue:6 : 1410-1424, 2012.
  19. V. Ludovini, G. Bellezza, L. Pistola, F. Bianconi, L. Di Carlo, A. Sidoni, A. Semeraro, R. Del Sordo, F. R.Tofanetti, M.G. Mameli , G. Daddi, A. Cavaliere, M. Tonato, L. Crinò, “High coexpression of both insulin-like growth factor receptor 1 (igfr-1) and epidermal growth factor receptor (egfr) is associated with shorter disease-free survival in resected non-small-cell lung cancer patients”, Annals of oncology 20 (5), 842-849, 2009.

Conference papers

  1. F. Bianconi, F. Patiti, E. Baldelli, L. Crinò, P. Valigi. “An approach for optimally extending mathematical models of signaling networks using omics data.” Engineering in Medicine and Biology Society (EMBC), 2015 37th Annual International Conference of the IEEE (pp. 6501-6504). IEEE.
  2. F. Bianconi, E. Baldelli, P. Valigi, “An approach to the conditional robustness problem for biochemical networks”, American Control Conference (ACC), 2014 (pp. 3417-3424). IEEE.
  3. F. Bianconi, V. Brunori, P. Valigi, F. Stracci, F. La Rosa, “Cancer Registry and information technology: a new management system for integrating Cancer Registry and Oncology Departments”, IEEE proceeding of Workshop on Health Care Management, Venice, Italy-February 18-20, 2010.
  4. F. Bianconi, M. Boccadoro, G. Lillacci, P. Valigi, “A strategy for parameter estimation for mRNA and protein dynamics”, Proceeding of International Conference on Computational and Systems Biology(ICCSB),Shanghai October 2009.
  5. F. Bianconi, G.Lillacci, P. Valigi. “A hybrid model of nucleotide excision repair in neoplastic diseases: the identification problem”, European Conference Control, 2007.

PhD Thesis

  • F. Bianconi. “Dynamic modeling, parameter estimation and experiment design in Systems Biology with applications to Oncology.” PhD Thesis, 2010 February.

Book chapters and monographs

  1. F. Bianconi, G. Lillacci, and P. Valigi, “Dynamic modeling and parameter identification for biological networks: application to the DNA damage and repair processes”, Handbook of Research on Computational and Systems Biology: Interdisciplinary Applications, 2011.
  2. F. Bianconi, P. Valigi, L. Crinò, V. Ludovini, S. Piattoni, A. Orleth, M. Tonato, “A Hybrid Model of Nucleotide Excision Repair in Neoplastic diseases and in vitro Experiments”, Dipartimento di Ingegneria Elettronica e dell’Informazione, Università di Perugia. Tech. Int. RT-003-06.
  3. MS. Petrucci, F. La Rosa, F. Bianconi, V. Brunori, F. Stracci, F. Dolciami, M. De Lucia, T. Marzulli, S. Ribiscini, A. Stigliani, “I Tumori multipli in Umbria.” CANCERSTAT UMBRIA, vol. 3; p. 439-488, ISSN: 2039-814X, 2012
  4. G. Baiocchi, SF. Gerli, G. Di Renzo, N. Buonora, L. Minelli, F. Bianconi, V. Brunori, F. La Rosa, F. Stracci, “I tumori dell’ovaio. CANCERSTAT UMBRIA”, vol. 3; p. 345-354, ISSN: 2039-814X, 2012
  5. N. Buonora, F. Bianconi, V. Brunori, F. La Rosa, F. Stracci, “La geografia del cancro in Umbria: incidenza 1978-2008.” CANCERSTAT UMBRIA, vol. 3; p. 375-435, ISSN: 2039-814X, 2012
  6. L. Mearini, E. Nunzi, M. Porena, G. Calagreti, F. Cioccoloni, S. Ferroni,F. Stracci, F. Bianconi, F. La Rosa, ”I tumori della vescica.” CANCERSTAT UMBRIA, vol. 3; p. 1-25, ISSN: 2039-814X, 2012
  7. A. Frenguelli, G. Ricci, MC. Cristi, N. Buonora, A. Monsignori, F. Stracci, F. Bianconi, V. Brunori V, F. La Rosa, “I tumori delle alte vie aero-digestive.” CANCERSTAT UMBRIA, vol. 3; p. 97-125, ISSN: 2039-814X, 2012
  8. L. Mearini, E. Nunzi, A. Zucchi, M. Porena, D. D’Alò, F. Stracci, F. Bianconi, F. La Rosa, “I tumori del rene.” CANCERSTAT UMBRIA, vol. 2; p. 1-5, ISSN: 2039-814X, 2011
  9. M. Marri, M. Petrella, N. Buonora, I. Bernardini, F. Stracci, F. Bianconi, F. La Rosa “Partecipazione al IV round dello screening citologico nella AUSL 2 dell'Umbria.” CANCERSTAT UMBRIA, vol. 2; p. 5-16, ISSN: 2039-814X, 2011
  10. E. Puxeddu, S. Romagnoli, R. Colella, G. Calagreti, F. Cioccoloni, S. Ferroni, F. Stracci, F. Bianconi, F. La Rosa, ”I tumori della tiroide.” CANCERSTAT UMBRIA, vol. 2; p. 1-10, ISSN: 2039-814X, 2011
  11. L. Mearini, E. Nunzi, A. Zucchi, M. Porena, D. D’Alò, F. Stracci, F. Bianconi, F. La Rosa, “I tumori del pene e del testicolo.” CANCERSTAT UMBRIA, vol. 2; p. 1-28, ISSN: 2039-814X, 2011


Department of Engineering, University of Perugia
06125 Perugia, Via G. Duranti, 93
Department of experimental Medicine, University of Perugia
06132 Perugia, Piazzale Settimio Gambuli
Edificio D, piano 0

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